PRODUCT INNOVATIONS
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STMicroelectronics and Debiotech
First prototypes of disposable insulin nanopump
Debiotech and STMicroelectronics introduced first evaluation prototypes
of a unique miniaturized insulin-delivery pump. The tiny device can be
mounted on a disposable skin patch to provide continuous insulin
infusion, enabling substantial advancements in the availability,
treatment efficiency and the quality of life of diabetes patients. The
breakthrough Nanopump, which relies on microfluidic MEMS
(Micro-Electro-Mechanical System) technology, has successfully passed
initial testing stages and is now ready to enter volume manufacturing.
The highly miniaturized disposable insulin pump combines
Debiotech’s expertise in insulin delivery systems with ST’s
strengths in manufacturing high-volume silicon-based microfluidic
devices. The Nanopump is less than one fourth the size of existing
insulin-pump devices and can be worn as a nearly invisible patch on the
skin.
Microfluidic technology also provides better control of the
administered insulin doses, more closely mimicking the natural
secretion of insulin from the pancreas, while detecting potential
malfunctions of the pump to further protect patients.
As a disposable device, manufactured using high-volume semiconductor
processing technologies, the MEMS-based Nanopump is also much more
affordable, allowing the patient or the health system to avoid the
substantial up-front investment typically associated with current pump
solutions.
Insulin pump therapy, or Continuous Subcutaneous Insulin Infusion
(CSII), is an increasingly attractive alternative to individual insulin
injections that must be administered several times a day. With CSII,
the patient is connected to a programmable pump including a storage
reservoir, from which insulin is infused into the tissue under the skin
throughout the day according to specific needs as programmed by the
patient.
The insulin Nanopump, developed by Debiotech and industrialized by ST,
represents the most advanced use of microfluidic MEMS technology in
diabetes treatment.
“The success of the initial prototype tests has moved the
revolutionary insulin Nanopump a step closer to market
availability,” said Benedetto Vigna, Group Vice President and
General Manager of ST’s MEMS and Healthcare, RF Transceivers and
Sensors Division. “Working with our key partner Debiotech, we are
readying a tiny piece of silicon that can make a huge difference to
millions of diabetes patients around the world.”
“This important milestone in the industrial production of the
insulin Nanopump is a key achievement toward the successful launch of a
new drug delivery device, combining the highest level of reliability
and performance with an previously unmet level of convenience and
safety for the patient,” said Dr. Frédéric Neftel,
President and CEO of Debiotech. “The collaboration with ST has
proven to be extremely efficient in time and achievements, allowing us
to now concentrate on a future partnership with a leading medical
device company who will be responsible to introduce the product on the
market.”
Additional information
There are almost 250 million people
affected by diabetes worldwide and the number is expected to grow over
the next decade due to population growth, ageing and life style.
Without proper treatment, diabetes can lead to cardiovascular disease,
kidney failure, blindness, nerve damage, and ultimately death. Diabetes
is a leading cause of death in most developed countries.
The
market for insulin pump therapy is growing rapidly: according to HSBC1,
the worldwide market for insulin pump therapy is expected to grow from
$800 million in 2004 to $1.6 billion by 2009.
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